Lion’s mane mushroom is a nootropic food with big benefits for the brain, gastrointestinal health, and immune system. Research shows that this mushroom can boost mental clarity, focus and concentration. It’s also a powerful anti-inflammatory, helping reduce symptoms of anxiety and depression. It can be found in fresh form in some supermarkets and specialty stores or in supplements. It has an umami flavor and a fleshy texture that can be cooked or added to soups. It’s also possible to grow it at home, with kits available online with seeds and instructions.

Fungal Finesse: Selecting the Best Lion’s Mane Mushroom

Best lion’s mane mushrooms contain beneficial compounds like helicene B and erinacines that support neuroprotection, increase nerve growth factor and promote healthy nervous systems, according to research (60). It may also help reduce blood pressure in some people, though more studies involving humans are needed. It could also benefit heart and blood vessel health, thanks to hericenone B’s ability to decrease the rate of clotting (61).

Other studies suggest that lion’s mane mushrooms may be helpful for autoimmune conditions, such as arthritis or rheumatoid arthritis, by helping the body repair damaged cells (62). It has also been shown to have cancer-fighting properties, although further research is needed on human participants (7, 8).

When selecting a lion’s mane supplement, it’s important to look for one that’s organic, third-party tested and made with fruiting bodies rather than mycelium. Check the label to make sure it doesn’t contain any added sugar, starch or fillers. A few options to consider include Lion’s Mane Mushroom Extract Powder by Malama Mushrooms, Four Sigmatic’s Think Elixir and the Organic Lion’s Mane Capsules by Host Defense.